Cunnings was a pawn of a conspiracy plot by Daniel Shaw and Clyde Decker to destroy Chuck Bartowski and his spy firm, Carmichael Industries. She is known for her extended torturing skills, although she "prefers to think of it more as an art form".
Her favorite interrogation technique has been electrocution with a device she dubs as "The Toy".
She targets Ellie and Captain Awesome as a leverage to convince Carmichael Industries into giving back the Omen Virus. Ellie manages to see through her fake kindness and realized that they were being kidnapped and escapes from her team. However, Chuck willingly surrenders himself thinking they still had Ellie. Sarah and Casey eventually arrive to rescue him and successfully captures her.
While under captivity at Castle, she reveals to General Beckman that she is indeed part of a conspiracy against Chuck - but no knowledge of who the mastermind is. To getting this info, she is ironically interrogated using her own torture device.
Cunnings has since been incarcerated by the CIA.
- Agent Cunnings is played by Rebecca Romijn, who is known for having portrayed Mystique in the first three films of the X-Men trilogy.